In een interview met Empire sprak regisseur Steven Spielberg over de kans dat we in de nabije toekomst Jurassic Park 4 en/of Indiana Jones 5 kunnen verwachten op het witte doek.

Over een vierde Jurassic Park zegt Spielberg: "The screenplay is being written right now by Mark Protosevich. I'm hoping that will come out in the next couple of years. We have a good story. We have a better story for four than we had for three..."

En over een vijfde Indiana Jones: "You have to ask George Lucas. George is in charge of breaking the stories. He's done it on all four movies. Whether I like the stories or not, George has broken all the stories." En: "He is working on Indy V. We haven't gone to screenplay yet, but he's working on the story. I'll leave it to George to come up with a good story."

Ook reageerde de regisseur op het bekritiseerde Indiana Jones and the Kingdom of the Crystal Skull (2008). Let op de SPOILER: "I sympathise with people who didn't like the MacGuffin because I never liked the MacGuffin. George and I had big arguments about the MacGuffin. I didn't want these things to be either aliens or inter-dimensional beings. But I am loyal to my best friend. When he writes a story he believes in - even if I don't believe in it - I'm going to shoot the movie the way George envisaged it."