Tijdens het interview maakte Shannen Doherty ook bekend dat ze in mei een borstamputatie heeft gehad. De actrice is heel open als het gaat om deze zware periode in haar leven. "The unknown is always the scariest part. Is the chemo going to work? Is the radiation going to work? You know, am I going to have to go through this again, or am I going to get secondary cancer? Everything else is manageable. Pain is manageable, you know living without a breast is manageable, it's the worry of your future and how your future is going to affect the people that you love."
Doherty vindt veel steun bij het team van doktoren, inclusief de chirurg die haar mastectomie heeft uitgevoerd. "He didn't want me to wake up with absolutely nothing. It was very important to him that I didn't have that experience, and so, he put an expander in, so I have a tiny something there. It's cute and sometimes we fill it up and make it bigger, and sometimes we reduce it. I'm being so personal right now. But I think a lot of women can probably go, 'Yeah, I've been through that.' It's great though, you get to pick out what size you want."
In februari 2015 kreeg de actrice te horen dat ze borstkanker heeft. Tot nu toe heeft de ze drie van de acht sessies chemotherapie gehad. Het verliezen van haar prachtige donkere lokken is voor de actrice nog het moeilijkste van alles. "After my second treatment, my hair was really matted, like in dreadlocks. And I went to try and brush it out, and it just fell out. I just remember holding onto huge clumps of my hair in my hands, and just running to my mom crying, like, 'My hair, my hair, my hair, my hair.' It was just shedding and it was driving me crazy. It was just clumps, and I was like, 'Just grab the kitchen scissors.' And my mom's like, 'Wait, wait, wait.' I'm just, like, 'Grab it.' She went and grabbed the kitchen scissors, and put it in a ponytail and she just chopped it off. And it was this cute little bob, but it wasn't enough, you know, it was falling out. We did stages. We did a pixie. And then we did a mohawk, which was my favorite look. And then finally, we had to get the shaver thing and just buzz it off."
De actrice geeft toe dat ze heel zelfbewust is over haar uiterlijk. Hoewel, boven alles, hoopt ze om andere die ook strijden tegen kanker te inspireren. "People don't realize that cancer -- yes, it ages you -- but also, you can balloon up from the various meds," aldus Shannen. "There are so many different reactions you have and so I just -- I didn't want someone to take a picture of me coming out of the grocery store and be like, 'Oh God, look at her.' I wanted to put it out there the way it felt the best for me to put it out there. And also, if I could help one person then it makes me go, 'Oh OK.' It's easier to live with having cancer if I know I'm helping at least one person."